Careers

TALENT DRIVES SUCCESS

We are looking for exceptionally talented individuals who share our passion for revolutionary science and commitment to changing the world by helping patients with serious diseases. We provide competitive and comprehensive benefits and are making REVOLUTION Medicines a great place to work.

CURRENT POSITIONS

REVOLUTION Medicines discovers and develops new drugs that translate frontier cancer targets through exceptional drug discovery delivering revolutionary medicines on behalf of cancer patients. Our innovative science draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

 

The Opportunity:

As a key player in our biology team, you will:

  • Integrate a deep knowledge of structural biology and biophysics to support discovery and development of novel cancer therapies.

  • Use biophysical techniques to perform cutting-edge in vitro studies to interrogate key scientific questions about established or candidate drug targets and therapeutic mechanisms.

  • Independently design and execute experimental strategies, using structural and biochemical techniques, to investigate target biology and support structure based drug design strategies.

  • Collaborate with medicinal chemists, biochemists, cell biologists, and pharmacologists to generate novel insights that fuel drug development as a member of a cross-functional project team.

  • Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.

  • Establish collaborations with leading academic research groups in the structural biology field.

  • Represent REVOLUTION Medicines with external organizations.

 

Required Experience, Skills, and Education:

  • Ph.D. degree in structural biology/biochemistry or a related discipline with demonstrable track record of achievement. Post-doctoral, or relevant industry experience, will be considered for the Scientist II level.

  • Strong track record of research productivity as evidenced by high-quality, impactful publications, in the field of biophysics.

  • Previous experience with X-ray crystallography and structural analysis is required. Knowledge of protein expression systems such as E. coli, mammalian, insect, would be an advantage.

  • Extensive hands on experience in modern protein purification and chromatography techniques. Knowledge of biochemical and biophysical assays (ITC, DSF, SPR) to characterize binding interactions would be an advantage.

  • Rigorous, quantitative, and detail-oriented experimentalist with a desire to continue in a laboratory-focused role.

  • Excellent written and verbal communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy, smaller company environment.

REVOLUTION Medicines discovers and develops new drugs that translate frontier cancer targets through exceptional drug discovery delivering revolutionary medicines on behalf of cancer patients. Our innovative science draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer. 

 

The Opportunity:

This is a unique opportunity for the right individual who has innate leadership and organizational skills, expertise in clinical oncology, and experience in designing and running exploratory-stage clinical trials. As the Medical Director, Clinical Development you will be accountable for the strategic design of Revolution Medicines early-stage clinical programs. Specifically, you will be responsible for:

  • Clinical strategy and clinical trial design particularly as it relates to how to best deploy our novel series of drugs in order to have the maximum impact for patients. This will be performed in collaboration with our multi-disciplinary Development Teams, consultants, external advisors, and the Chief Medical Officer.

  • Generation of clinical and regulatory documents that are required for the initiation and conduct of clinical trials, particularly phase 1b and 2 trials in oncology.

  • Data review, interpretation, and reporting of clinical trials.

  • Keeping up to date in the relevant disease areas, including anticipating changes in standard of care and the competitive environment, so as to be perceived as the disease expert for the company.

  • Maintaining a working knowledge of the relevant regulatory landscape.

  • Maintaining a relationship with, and representing the company to, external experts in the field.

  • For the right candidate, there is an opportunity to run a multi-disciplinary development team.

 

Required Experience, Skills, and Education:

  • MD degree or equivalent, with board certification in oncology or related discipline.

  • Hands-on experience of designing and running early-stage clinical trials.

  • A demonstrable record of strong leadership and teamwork.

  • Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy environment.

  • Excellent written and verbal communication skills.

  • Ability to act as an excellent ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Industry experience would be helpful but not essential. For the right candidate this role could provide an entry in to the Pharmaceutical/Biotech industry from academia.

REVOLUTION Medicines discovers and develops new drugs that translate frontier cancer targets through exceptional drug discovery delivering revolutionary medicines on behalf of cancer patients. Our innovative science draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer. 

 

The Opportunity:

As a member of the cancer pharmacology team you will:

  • Be a critical contributor to the cancer biology organization and multi-disciplinary research project teams.

  • Integrate a deep knowledge of oncogenic signaling pathways into the design and execution of experiments related to the discovery of novel anti-cancer agents, including but not restricted to:

  • Novel oncology pathway inhibitors

  • Combination strategies

  • Preclinical pharmacodynamic studies

  • Be accountable for the conduct of cutting-edge tumor biology research, integrating knowledge from oncology, cell biology and human genetics, to support development of novel therapies using innovative technologies and approaches.

  • Establish and manage relationships with external collaborators in cancer biology field in basic and clinical sciences.

  • Manage and analyze experimental data and present results at internal meetings and scientific conferences.

  • The post-holder may be required to manage or supervise other scientific or technical personnel.

 

Required Experience, Skills, and Education:

  • Ph.D. degree in pharmacology, oncology, cell biology or a related discipline, with at least 1-3 years of post-doctoral and at least 3 years of relevant industry experience in cancer discovery biology from target selection to late preclinical evaluation.

  • Deep expertise in oncogenic signaling pathways is important. Expertise in the PI3K/mTOR pathway would be an advantage.

  • Strong track record of research productivity as evidenced by high-quality, impactful publications.

  • Demonstrated experience as project leader of multidisciplinary project team.

  • Strategic thinker with proven leadership skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Experience working with external collaborators in cancer biology field in basic and/or clinical science.

  • Rigorous, quantitative and detail-oriented experimentalist.

  • Excellent written and verbal communication skills.

  • Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy, small company environment. 

REVOLUTION Medicines discovers and develops new drugs that translate frontier cancer targets through exceptional drug discovery delivering revolutionary medicines on behalf of cancer patients. Our innovative science draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer. 

 

The Opportunity:

As a key player in our biology team, you will:

  • Integrate a deep knowledge of tumor immunology and immunotherapy to support discovery and development of novel immuno-oncology therapies

  • Use immunology techniques to perform cutting-edge studies, in vitro and in vivo, to interrogate key scientific questions about established or candidate drug targets and therapeutic mechanisms

  • Independently design and execute experimental strategies, using cellular and molecular immunological techniques, to investigate target biology and therapeutic mechanisms of action in in vivo immuno-oncology models.

  • Collaborate with biochemists, cell biologists and pharmacologists to generate novel insights that fuel drug development as a member of a cross-functional project team.

  • Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.

  • Establish collaborations with leading academic research groups in the tumor immunology field.

  • Represent REVOLUTION Medicines with external organizations.

 

Required Experience, Skills, and Education:

  • Ph.D. degree in immunology, cancer biology or a related discipline with demonstrable track record of excellence in tumor immunology and/or immunotherapy (Scientist I). Post-doctoral, or relevant industry experience, (Scientist II) will be considered but not necessary.

  • Strong track record of research productivity as evidenced by high-quality, impactful publications, in the field of tumor immunology.

  • Previous experience with in vivo tumor growth assays is required. Knowledge of models that interrogate and modulate cells and mediators of the innate and adaptive immune system would be an advantage.

  • Extensive hands on experience in ‘state of the art’ immunology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional assays, imaging, cell biology and molecular biology. Knowledge of manipulation of human PBMCs and functional assays with human immune cells would be an advantage.

  • Rigorous, quantitative and detail-oriented experimentalist with a desire to continue in a laboratory-focused role

  • Excellent written and verbal communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy start-up environment. 

JOIN THE REVOLUTION!

We offer a dynamic, collaborative and scientifically challenging environment plus an excellent benefits package. To be considered for one of these exciting career opportunities, please forward your resume with a cover letter to talent@revolutionmedicines.com.

REVOLUTION Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status.

Note to Employment Agencies: Please do not forward any agency resumes as REVOLUTION Medicines is not responsible for any fees related to resumes that are unsolicited.